Twin-twin transfusion syndrome: neurodevelopmental screening test.

Twin-twin transfusion syndrome: neurodevelopment of infants treated with laser surgery.

OBJECTIVE To assess the neurodevelopmental functions of survivors of twin-twin transfusion syndrome (TTTS) treated by fetoscopic laser coagulation (FLC), during the first year of life, comparing them to a control group; and to verify the influence of specific variables on neurodevelopment. METHOD This was a prospective, longitudinal study. The sample comprised 33 monochorionic diamniotic twin...

Long-term neurodevelopmental outcome in twin-to-twin transfusion syndrome.

OBJECTIVE The purpose of this study was to determine the long-term neurodevelopmental outcome in children after twin-to-twin transfusion syndrome. STUDY DESIGN Maternal and neonatal medical records of all twin-to-twin transfusion syndrome patients who were admitted to our center between 1990 and 1998 were reviewed. Neurologic and mental development at school age was assessed during a home vis...

Twin-to-twin transfusion syndrome: from placental anastomoses to long-term neurodevelopmental outcome

Cerebral injury and neurodevelopmental impairment after amnioreduction versus laser surgery in twin-twin transfusion syndrome: a systematic review and meta-analysis.

OBJECTIVE To estimate the odds of severe cerebral injury and long-term neurodevelopmental impairment in monochorionic twins treated with amnioreduction versus laser surgery for twin-twin transfusion syndrome. METHODS A systematic review and meta-analysis of studies on cerebral injury and long-term impairment after amnioreduction versus laser surgery were conducted. Odds ratios (OR) with their...

Twin-twin transfusion syndrome: where do we go from here?

Management of Twin-Twin Transfusion Syndrome (TTTS) is one of the most challenging clinical problems concerning multiple gestations. The pathophysiology of TTTS and Quintero staging system are described. The importance of fetal echocardiograms in assessing prognosis and response to therapy is highlighted. Treatment modalities, particularly amnioreduction, microseptostomy, and fetoscopic laser p...